Title : Essential role for the Menkes ATPase in activation of extracellular superoxide dismutase: implication for vascular oxidative stress.

Pub. Date : 2006 Feb

PMID : 16371425






3 Functional Relationships(s)
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1 Extracellular superoxide dismutase (SOD3), a secretory copper enzyme, plays an important role in atherosclerosis and hypertension by modulating the levels of extracellular superoxide anion (O2*-) in the vasculature. Superoxides superoxide dismutase 3, extracellular Mus musculus
2 Extracellular superoxide dismutase (SOD3), a secretory copper enzyme, plays an important role in atherosclerosis and hypertension by modulating the levels of extracellular superoxide anion (O2*-) in the vasculature. Superoxides superoxide dismutase 3, extracellular Mus musculus
3 In conclusion, vascular MNK plays an essential role in full activity of SOD3 through transporting copper to SOD3 in the TGN, thereby regulating O2*- levels in the vasculature. Superoxides superoxide dismutase 3, extracellular Mus musculus