Title : Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes.

Pub. Date : 2006 Jan

PMID : 16354686






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Clearance of both superoxide and H2O2 from within the endosomal compartment significantly abrogated IL-1beta-dependent IKK and NF-kappaB activation. Superoxides interleukin 1 beta Homo sapiens
2 Small interfering RNAs to either MyD88 or Rac1 inhibited IL-1beta induction of endosomal superoxide and NF-kappaB activation. Superoxides interleukin 1 beta Homo sapiens