Title : Rho-kinase mediates spinal nitric oxide formation by prostaglandin E2 via EP3 subtype.

Pub. Date : 2005 Dec 9

PMID : 16188227






1 Functional Relationships(s)
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1 We recently demonstrated that continuous production of nitric oxide (NO) by neuronal NO synthase (nNOS) following phosphorylation of myristoylated alanine-rich C-kinase substrate (MARCKS) and NMDA receptor NR2B subunits is essential for neuropathic pain. Nitric Oxide myristoylated alanine rich protein kinase C substrate Homo sapiens