Title : Frequent mutations of human Mad2, but not Bub1, in gastric cancers cause defective mitotic spindle checkpoint.

Pub. Date : 2005 Oct 15

PMID : 16112690

1 Functional Relationships(s)
Compound Name
Protein Name
1 Overexpression of mutant Mad2 in HeLa cells led to the appearance of aneuploid cells in the presence of nocodazole, and this indicated that these mutations caused a defect in MAD2 protein. Nocodazole mitotic arrest deficient 2 like 1 Homo sapiens