Title : Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal.

Pub. Date : 2005 Aug 23

PMID : 16103361






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Acetyl-CoA carboxylases (ACC1 and ACC2) catalyze the carboxylation of acetyl-CoA to form malonyl-CoA, an intermediate metabolite that plays a pivotal role in the regulation of fatty acid metabolism. Fatty Acids acetyl-Coenzyme A carboxylase alpha Mus musculus
2 Our previous results of the ACC2 knockout mice and current studies of ACC1 knockout mice further confirm our hypotheses that malonyl-CoA exists in two independent pools, and that ACC1 and ACC2 have distinct roles in fatty acid metabolism. Fatty Acids acetyl-Coenzyme A carboxylase alpha Mus musculus
3 Our previous results of the ACC2 knockout mice and current studies of ACC1 knockout mice further confirm our hypotheses that malonyl-CoA exists in two independent pools, and that ACC1 and ACC2 have distinct roles in fatty acid metabolism. Fatty Acids acetyl-Coenzyme A carboxylase alpha Mus musculus