Title : Lipoprotein-associated phospholipase A2 as a target of therapy.

Pub. Date : 2005 Aug

PMID : 15990594






1 Functional Relationships(s)
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1 Lp-PLA2 is well placed, whether on an oxidation susceptible LDL particle or in the highly oxidative environment of an advanced rupture-prone plaque, to hydrolyse oxidized phospholipid and generate significant quantities of the two pro-inflammatory mediators, lysophosphatidylcholine and oxidized nonesterified fatty acid. Fatty Acids, Nonesterified phospholipase A2 group VII Homo sapiens