Title : Protein trafficking abnormalities: a new mechanism in drug-induced long QT syndrome.

Pub. Date : 2005 May

PMID : 15711590






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The drug pentamidine, at near therapeutic concentrations that do not cause direct KCNH2 channel block, disrupts normal KCNH2 channel protein processing and maturation to reduce its surface membrane expression. Pentamidine potassium voltage-gated channel subfamily H member 2 Homo sapiens