Title : Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA.

Pub. Date : 2004 Dec 21

PMID : 15595846






1 Functional Relationships(s)
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1 This finding establishes that mNEIL1 and its functional homologue hNEIL1 possess common substrates, namely, 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine. 2,6-diamino-4-hydroxy-5-formamidopyrimidine nei like DNA glycosylase 1 Homo sapiens