Title : Metabolism of vitamin D3 by cytochromes P450.

Pub. Date : 2005 Jan 1

PMID : 15574355






2 Functional Relationships(s)
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1 Enzymatic studies on substrate specificity of CYP27B1 suggest that the 1alpha-hydroxylase activity of CYP27B1 requires the presence of 25-hydroxyl group of vitamin D3 and is enhanced by 24-hydroxyl group while the presence of 23-hydroxyl group greatly reduced the activity. Cholecalciferol cytochrome P450 family 27 subfamily B member 1 Homo sapiens
2 Enzymatic studies on substrate specificity of CYP27B1 suggest that the 1alpha-hydroxylase activity of CYP27B1 requires the presence of 25-hydroxyl group of vitamin D3 and is enhanced by 24-hydroxyl group while the presence of 23-hydroxyl group greatly reduced the activity. Cholecalciferol cytochrome P450 family 27 subfamily B member 1 Homo sapiens