Title : Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation.

Pub. Date : 2005 Jan 7

PMID : 15569826






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Transfection of a dominant-negative (RacN17) and constitutively active Rac1 mutant (RacV12) indicated that ANP-induced superoxide generation and MKP-1 expression are mediated via Rac1 activation. Superoxides Rac family small GTPase 1 Homo sapiens
2 Transfection of a dominant-negative (RacN17) and constitutively active Rac1 mutant (RacV12) indicated that ANP-induced superoxide generation and MKP-1 expression are mediated via Rac1 activation. Superoxides Rac family small GTPase 1 Homo sapiens