Title : Activator protein-1 signalling pathway and apoptosis are modulated by poly(ADP-ribose) polymerase-1 in experimental colitis.

Pub. Date : 2004 Dec

PMID : 15554929






1 Functional Relationships(s)
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1 In wild-type mice, TNBS treatment resulted in colonic ulceration and marked apoptosis, which was associated with decreased colon content of the antiapoptotic protein Bcl-2, whereas the proapoptotic Bax was unchanged. Trinitrobenzenesulfonic Acid B cell leukemia/lymphoma 2 Mus musculus