Title : Peroxisome proliferator-activated receptor alpha induces NADPH oxidase activity in macrophages, leading to the generation of LDL with PPAR-alpha activation properties.

Pub. Date : 2004 Dec 10

PMID : 15539630






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The increase in ROS production was not attributable to inherent prooxidant effects of the PPAR-alpha agonists tested, but was mediated by PPAR-alpha, because the effects were lost in bone marrow-derived macrophages from PPAR-alpha-/- mice. Reactive Oxygen Species peroxisome proliferator activated receptor alpha Mus musculus
2 The increase in ROS production was not attributable to inherent prooxidant effects of the PPAR-alpha agonists tested, but was mediated by PPAR-alpha, because the effects were lost in bone marrow-derived macrophages from PPAR-alpha-/- mice. Reactive Oxygen Species peroxisome proliferator activated receptor alpha Mus musculus
3 The increase in ROS production was not attributable to inherent prooxidant effects of the PPAR-alpha agonists tested, but was mediated by PPAR-alpha, because the effects were lost in bone marrow-derived macrophages from PPAR-alpha-/- mice. Reactive Oxygen Species peroxisome proliferator activated receptor alpha Mus musculus