Title : Utilization of peptide carrier system to improve intestinal absorption: targeting prolidase as a prodrug-converting enzyme.

Pub. Date : 1992 Feb

PMID : 1545347






1 Functional Relationships(s)
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1 The enzymatic hydrolysis by prolidase of substrates for the peptide transporter L-alpha-methyldopa-pro and several dipeptide analogues without an N-terminal alpha-amino group (phenylpropionylproline, phenylacetylproline, N-benzoylproline, and N-acetylproline) was investigated. L-Proline, 1-(1-oxo-3-phenylpropyl)- peptidase D Homo sapiens