Title : Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120.

Pub. Date : 2004 Aug 30

PMID : 15342104






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1 Furthermore, this activation, as measured by TNF-alpha and nitric oxide (NO) release, is synergistically attenuated through the alpha7 nAChR and p44/42 MAPK system by pretreatment with nicotine, and the cholinesterase inhibitor, galantamine. Nicotine tumor necrosis factor Homo sapiens