Title : Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide.

Pub. Date : 2004 Apr 20

PMID : 15285800

1 Functional Relationships(s)
Compound Name
Protein Name
1 Bioassays of hippocampal neurons with the microglia-conditioned medium indicated that Abeta elevated a NMDA receptor agonist that was sensitive to an antagonist of the D-serine/glycine site (5,7-dicholorokynurenic acid; DCKA) and to enzymatic degradation of D-amino acids by D-amino acid oxidase (DAAOx). Glycine amyloid beta precursor protein Homo sapiens