Title : [Impairment of IRS-2 signaling in rat insulinoma INS-1 cells by nelfinavir].

Pub. Date : 2004 Jul

PMID : 15269981






2 Functional Relationships(s)
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1 RESULT: Nelfinavir decreased insulin stimulated phosphorylation of IRS-2 and Akt-Thr(308) in a dose-dependent manner; for 10 micromol/L of nelfinavir, the decrease was 52% and 55%, respectively. Nelfinavir AKT serine/threonine kinase 1 Rattus norvegicus
2 RESULT: Nelfinavir decreased insulin stimulated phosphorylation of IRS-2 and Akt-Thr(308) in a dose-dependent manner; for 10 micromol/L of nelfinavir, the decrease was 52% and 55%, respectively. Nelfinavir AKT serine/threonine kinase 1 Rattus norvegicus