Title : Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death.

Pub. Date : 2004 Jul

PMID : 15132987






1 Functional Relationships(s)
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1 Blocking GSK3beta activity by selective inhibitors (lithium, TDZD-8, and L803-mts) prevented 6-OHDA-induced cleavage of caspase-3 and poly(ADP-ribose) polymerase (PARP), DNA fragmentations and cell death. Oxidopamine caspase 3 Homo sapiens