Title : Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model.

Pub. Date : 2004 May

PMID : 15131570






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ciglitazone, a PPAR-gamma agonist, was administered by means of nebulization alone at the time of antigen challenge or by means of gavage and nebulization. ciglitazone peroxisome proliferator activated receptor gamma Mus musculus
2 Treatments with both ciglitazone and GW9662, a specific antagonist, were also performed to verify that ciglitazone"s effects were mediated through PPAR-gamma activation. ciglitazone peroxisome proliferator activated receptor gamma Mus musculus
3 Treatment with ciglitazone reduced PPAR-gamma levels in the lung, whereas combined treatment with GW9662 abrogated this inhibition. ciglitazone peroxisome proliferator activated receptor gamma Mus musculus