Pub. Date : 2004 Jul
PMID : 15121760
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The ATP binding cassette (ABC) half-transporters ABCG5 and ABCG8 facilitate biliary and intestinal removal of neutral sterols. | Sterols | ATP binding cassette subfamily G member 8 | Homo sapiens |
| 2 | These results demonstrate that LRH-1 is a positive transcription factor for ABCG5 and ABCG8 and, in conjunction with studies on LRH-1 activation of other promoters, identify LRH-1 as a "master regulator" for genes involved in sterol and bile acid secretion from liver and intestine. | Sterols | ATP binding cassette subfamily G member 8 | Homo sapiens |