Title : Generation of highly stable IL-18 based on a ligand-receptor complex structure.

Pub. Date : 2004 Apr 23

PMID : 15047165






1 Functional Relationships(s)
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1 Here we have generated a highly stable hIL-18 with replacement of cysteine by serine based on the tertiary structure and the binding mechanism, retaining the biological activity. Cysteine interleukin 18 Homo sapiens