Pub. Date : 1992 Nov 4
PMID : 1480164
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The specificity of labeling of AdoMetDC by this procedure was confirmed by the prevention of 35S-decarboxylated S-adenosylmethionine (AdoMet) binding in the presence of specific AdoMetDC inhibitors [either methylglyoxal bis(guanylhydrazone (MGBG), a reversible inhibitor, or 5"-deoxy-5"-[(2-hydrazinoethyl)methylamino]adenosine (MHZEA), an irreversible inactivator]. | Mitoguazone | adenosylmethionine decarboxylase 1 | Homo sapiens |
| 2 | The specificity of labeling of AdoMetDC by this procedure was confirmed by the prevention of 35S-decarboxylated S-adenosylmethionine (AdoMet) binding in the presence of specific AdoMetDC inhibitors [either methylglyoxal bis(guanylhydrazone (MGBG), a reversible inhibitor, or 5"-deoxy-5"-[(2-hydrazinoethyl)methylamino]adenosine (MHZEA), an irreversible inactivator]. | Mitoguazone | adenosylmethionine decarboxylase 1 | Homo sapiens |
| 3 | As compared to human AdoMetDC, the trypanosomal enzyme showed weaker binding to a column of MGBG-Sepharose and also was significantly less sensitive to inhibition by MGBG and its congener ethylglyoxal bis(guanylhydrazone) (EGBG). | Mitoguazone | adenosylmethionine decarboxylase 1 | Homo sapiens |
| 4 | As compared to human AdoMetDC, the trypanosomal enzyme showed weaker binding to a column of MGBG-Sepharose and also was significantly less sensitive to inhibition by MGBG and its congener ethylglyoxal bis(guanylhydrazone) (EGBG). | Mitoguazone | adenosylmethionine decarboxylase 1 | Homo sapiens |