Title : Interleukin 7 induces the growth of breast cancer cells through a wortmannin-sensitive pathway.

Pub. Date : 2004 Jan

PMID : 14716795






1 Functional Relationships(s)
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1 The maximum effects were observed after incubation for 72 h. The stimulatory effect of IL-7 on cell growth was completely eliminated in the presence of wortmannin (P = 0.001 and P = 0.003 versus no inhibitor in MDA MB-231 and MCF-7 cells, respectively) and JAK-3 inhibitor 1 (P < 0.001 versus no inhibitor in both cell lines), but not in the presence of piceatanol and AG 490. 3,3',4,5'-tetrahydroxystilbene interleukin 7 Homo sapiens