Title : A fluorescent hPept1 transporter substrate for uptake screening.

Pub. Date : 2003 Nov

PMID : 14661916






2 Functional Relationships(s)
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1 RESULTS: In HeLa/hPept1 cells, [3H]Gly-Sar uptake was significantly inhibited by Lys-FITC-OCH3 (74%) but not by FITC-Val-OCH3 (22%). Glycine solute carrier family 15 member 1 Homo sapiens
2 Also, Lys-FITC-OCH3 (100 microM) uptake in HeLa/hPept1 and Caco-2 cells was reduced by 77% and 80%, respectively, in the presence of 1 mM Gly-Sar. Glycine solute carrier family 15 member 1 Homo sapiens