Title : Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease.

Pub. Date : 2003 Nov

PMID : 14561585






2 Functional Relationships(s)
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1 The abundance of the oligopeptide transporter (Pept-1) in the brush-border membrane of the intestinal epithelium is the central mechanism for regulation of transport of products of protein digestion (dipeptides and tripeptides) and peptidomimetic drugs (for example, beta-lactam antibiotics). Dipeptides solute carrier family 15 member 1 Homo sapiens
2 In the case of dipeptides, epidermal growth factor, and thyroid hormone, there are parallel changes in the gene expression brought about by alteration of transcription and/or stability of Pept-1 mRNA. Dipeptides solute carrier family 15 member 1 Homo sapiens