Title : Activation of peroxisome proliferator-activated receptor-alpha protects the heart from ischemia/reperfusion injury.

Pub. Date : 2003 Nov 11

PMID : 14557369






2 Functional Relationships(s)
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1 A highly selective and potent PPAR-alpha agonist, GW7647, was administered by mouth for 2 days, and the third dose was given 1 hour before ischemia. GW 7647 peroxisome proliferator activated receptor alpha Mus musculus
2 Cardioprotection by GW7647 was completely abolished in PPAR-alpha-null mice. GW 7647 peroxisome proliferator activated receptor alpha Mus musculus