Title : Localization of an antithrombin exosite that promotes rapid inhibition of factors Xa and IXa dependent on heparin activation of the serpin.

Pub. Date : 2003 Dec 19

PMID : 14532267

1 Functional Relationships(s)
Compound Name
Protein Name
1 All chimeras bound heparin with a high affinity similar to wild-type, underwent heparin-induced fluorescence changes indicative of normal conformational activation, and were able to form SDS-stable complexes with thrombin, factor Xa, and factor IXa and inhibit these proteases with stoichiometries minimally altered from those of wild-type antithrombin. Sodium Dodecyl Sulfate serpin family C member 1 Homo sapiens