Title : The inhibition of blood coagulation by heparins of different molecular weight is caused by a common functional motif--the C-domain.

Pub. Date : 2003 May

PMID : 12871355






1 Functional Relationships(s)
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1 RESULTS: The antithrombin activity and the effects on TG and APTT are primarily determined by the concentration of C-domain and independent of the source material (UFH or LMWH) or Mr. High Mr fractions (>15 000) are less active, probably through interaction with non-antithrombin plasma proteins. Heparin, Low-Molecular-Weight serpin family C member 1 Homo sapiens