Title : Immunomodulatory effects of tetrachlorobenzoquinone, a reactive metabolite of hexachlorobenzene.

Pub. Date : 2003 Jun

PMID : 12807351






3 Functional Relationships(s)
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1 We have assessed in the reporter antigen-popliteal lymph node assay whether HCB or TCHQ and TCBQ are able to induce a 2,4,6-trinitrophenyl (TNP) specific IgG1 response to the T cell-independent antigen TNP-Ficoll, which is indicative of neoantigen specific T cell help. 2,3,5,6-tetrachlorohydroquinone LOC105243590 Mus musculus
2 In the secondary PLNA, only mice primed with TCHQ and challenged with TCHQ together with TNP-Ficoll showed a significant increase in TNP specific IgG1 ASC. 2,3,5,6-tetrachlorohydroquinone LOC105243590 Mus musculus
3 In the secondary PLNA, only mice primed with TCHQ and challenged with TCHQ together with TNP-Ficoll showed a significant increase in TNP specific IgG1 ASC. 2,3,5,6-tetrachlorohydroquinone LOC105243590 Mus musculus