Title : Effects of the glutamate carboxypeptidase II (GCP2 1561C>T) and reduced folate carrier (RFC1 80G>A) allelic variants on folate and total homocysteine levels in kidney transplant patients.

Pub. Date : 2003 Jun

PMID : 12753319






2 Functional Relationships(s)
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1 RESULTS: The allele frequency for GCP2 1561C>T was 0.05, and 0.43 for RFC1 80G>A. Heterozygosity or homozygosity for GCP2 1561C>T was associated with higher folate plasma levels compared to patients without mutation (P < 0.0001), while RFC1 80G>A showed no influence. Folic Acid folate hydrolase 1 Homo sapiens
2 CONCLUSION: We conclude that GCP2 1561C>T is associated with elevated folate levels. Folic Acid folate hydrolase 1 Homo sapiens