Title : Arsenic trioxide induces apoptosis in cells of MOLT-4 and its daunorubicin-resistant cell line via depletion of intracellular glutathione, disruption of mitochondrial membrane potential and activation of caspase-3.

Pub. Date : 2003 Jul

PMID : 12750841






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Decreasing GSH with BSO potentiated As(2)O(3)-mediated growth inhibition, disruption of MMP, activation of caspase-3 and apoptosis of cells. Glutathione caspase 3 Homo sapiens