Title : Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury.

Pub. Date : 2003 May

PMID : 12744489






1 Functional Relationships(s)
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1 Male Sprague-Dawley rats were administrated the serine protease inhibitor (6-amidino-2-naphthyl p-guanidinobenzoate dimethanesulfate, Nafamostat) either intraluminally into the gut or intravenously after a laparotomy (trauma) and then subjected to 90 min of hemorrhagic shock (T/HS) or sham shock (T/SS). nafamostat kallikrein 1-related peptidase C8 Rattus norvegicus