Title : Glutamate-115 renders specificity of human 11beta-hydroxysteroid dehydrogenase type 2 for the cofactor NAD+.

Pub. Date : 2003 Mar 28

PMID : 12706305






2 Functional Relationships(s)
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Protein Name
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1 Glutamate-115 renders specificity of human 11beta-hydroxysteroid dehydrogenase type 2 for the cofactor NAD+. NAD hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens
2 Thus, predictions using the 3D-model combined with analysis of mutants allowed the identification of residues critical for NAD(+)-dependent activity of 11beta-HSD2. NAD hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens