Title : Nicotinic acetylcholine receptor subunits and receptor activity in the epithelial cell line HT29.

Pub. Date : 2003 Mar 28

PMID : 12628462






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the present study we have used RT-PCR to investigate nicotinic acetylcholine receptor (nAChR) subunit expression, and studied the effect of nicotine on TNFalpha-induced cytokine (IL-8) release in the epithelial cell line HT29. Nicotine tumor necrosis factor Homo sapiens
2 Nicotine significantly inhibited TNFalpha-induced IL-8 release in a concentration related manner with peak inhibition occurring at 10(-7) M (2.39 +/- 0.78 ng ml(-1), n = 5). Nicotine tumor necrosis factor Homo sapiens