Pub. Date : 2003 Mar 15
PMID : 12626713
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We show here that both Mec1 and Tel1 regulate the checkpoint response following phleomycin treatment. | Phleomycins | protein kinase MEC1 | Saccharomyces cerevisiae S288C |
2 | MEC1 is required for Rad53 phosphorylation and cell-cycle progression delay following phleomycin treatment in G1, S or G2/M phases. | Phleomycins | protein kinase MEC1 | Saccharomyces cerevisiae S288C |
3 | In addition, the tel1Delta mutation enhances the mec1 defect in activation of the phleomycin-induced checkpoint pathway in S phase. | Phleomycins | protein kinase MEC1 | Saccharomyces cerevisiae S288C |