Title : Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins.

Pub. Date : 2003 Mar 1

PMID : 12615696

1 Functional Relationships(s)
Compound Name
Protein Name
1 Ciglitazone and 9cRA increased CD36 mRNA (up to 4-fold); however, uptake of [125I]oxLDL was only modestly enhanced (up to 1.8-fold) becaues of a concomitant PPARgamma:RXR-induced decrease in SRAI/II activity (up to 40%). ciglitazone peroxisome proliferator activated receptor gamma Mus musculus