Title : Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor.

Pub. Date : 2003 Apr

PMID : 12594180






4 Functional Relationships(s)
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1 Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor. Dinoprostone interleukin 2 Homo sapiens
2 In this paper, we show that prostaglandin E2 (PGE2), a potent inflammatory mediator, inhibits IL-2 production in human lymphocytes by a cyclic AMP (cAMP)-dependent mechanism. Dinoprostone interleukin 2 Homo sapiens
3 In this paper, we show that prostaglandin E2 (PGE2), a potent inflammatory mediator, inhibits IL-2 production in human lymphocytes by a cyclic AMP (cAMP)-dependent mechanism. Dinoprostone interleukin 2 Homo sapiens
4 In this model, melatonin counteracts the effects of PGE2 on IL-2 and cAMP production. Dinoprostone interleukin 2 Homo sapiens