Title : The radical model of Alzheimer's disease: specific recognition of Gly29 and Gly33 by Met35 in a beta-sheet model of Abeta: an ONIOM study.

Pub. Date : 2002 Aug

PMID : 12446930






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the present work, QM/MM and Amber calculations reveal that self assembly of antiparallel beta-sheet which brings Met35 into the required close proximity to a glycine residue is more likely if the residue is Gly29 or Gly33, than any of the other four glycine residues of Abeta. Glycine amyloid beta precursor protein Homo sapiens
2 In the present work, QM/MM and Amber calculations reveal that self assembly of antiparallel beta-sheet which brings Met35 into the required close proximity to a glycine residue is more likely if the residue is Gly29 or Gly33, than any of the other four glycine residues of Abeta. Glycine amyloid beta precursor protein Homo sapiens