Title : Alternative splicing of a beta4 subunit proline-rich motif regulates voltage-dependent gating and toxin block of Cav2.1 Ca2+ channels.

Pub. Date : 2002 Nov 1

PMID : 12417658






1 Functional Relationships(s)
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1 The models (1) reveal that alternative splicing of the beta4 N terminus results in dramatic differences in surface charge distribution and (2) localize the proline-rich motif of beta4b to an extended arm structure that flanks what would be the equivalent of a highly modified PSD-95 carboxylate binding loop. Proline discs large MAGUK scaffold protein 4 Homo sapiens