Title : A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis.

Pub. Date : 2002 Oct 7

PMID : 12370259






1 Functional Relationships(s)
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1 The inhibitory effect of IL-6 on Fas ligand expression during activation-induced cell death (AICD) was augmented in gp130(F759/F759) T cells in a manner dependent on the tyrosine residues of gp130 required for signal transducer and activator of transcription 3 activation. Tyrosine interleukin 6 Mus musculus