Title : Antithrombin 'DREUX' (Lys 114Glu): a variant with complete loss of heparin affinity.

Pub. Date : 2002 Sep

PMID : 12353073






1 Functional Relationships(s)
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1 Here we report the finding of a new natural antithrombin mutation that confirms the critical contribution of lysine 114 to the binding of the core heparin pentasaccharide, with the replacement of lysine 114 by glutamate causing a complete loss in affinity. Lysine serpin family C member 1 Homo sapiens