Title : [Screening of mutations in genes of pro-opiomelanocortin in patients with constitutional exogenous obesity].

Pub. Date : 2002 Jan-Feb

PMID : 12068494






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 (GGGCCC) in codon 176 inducing the insertion of two amino acid residues (Arg-Ala) in POMC and nonsense mutation (G-7316-T) in codon 180 of gamma-LTH coding region of the same DNA chain were identified in 4 women (5.8%) out of 69 patients with morbid obesity (BMI 40-53 kg/m2). Arginine proopiomelanocortin Homo sapiens