Pub. Date : 2002 Mar 5
PMID : 11863435
4 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | Steady-state inhibition data show that huprine X binds to human AChE and Torpedo AChE 28- and 54-fold, respectively, more tightly than tacrine. | huprine | acetylcholinesterase (Cartwright blood group) | Homo sapiens | ||
2 | Steady-state inhibition data show that huprine X binds to human AChE and Torpedo AChE 28- and 54-fold, respectively, more tightly than tacrine. | huprine | acetylcholinesterase (Cartwright blood group) | Homo sapiens | ||
3 | Furthermore, both tacrine and huprine X bind more tightly to Torpedo than to human AChE, suggesting that their quinoline substructures interact better with Phe330 than with Tyr337, the corresponding residue in the human AChE structure. | huprine | acetylcholinesterase (Cartwright blood group) | Homo sapiens | ||
4 | Furthermore, both tacrine and huprine X bind more tightly to Torpedo than to human AChE, suggesting that their quinoline substructures interact better with Phe330 than with Tyr337, the corresponding residue in the human AChE structure. | huprine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |