Title : Interaction of the CC-chemokine RANTES with glycosaminoglycans activates a p44/p42 mitogen-activated protein kinase-dependent signaling pathway and enhances human immunodeficiency virus type 1 infectivity.

Pub. Date : 2002 Mar

PMID : 11836402






2 Functional Relationships(s)
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1 Interaction of the CC-chemokine RANTES with glycosaminoglycans activates a p44/p42 mitogen-activated protein kinase-dependent signaling pathway and enhances human immunodeficiency virus type 1 infectivity. Glycosaminoglycans C-C motif chemokine ligand 5 Homo sapiens
2 Here we show that activation of both PTK and MAPK is involved in the enhancement of HIV-1 infectivity caused by RANTES in cells that lack GPCRs for RANTES but which express GAGs. Glycosaminoglycans C-C motif chemokine ligand 5 Homo sapiens