Title : Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells.

Pub. Date : 2002 Mar 22

PMID : 11792699






1 Functional Relationships(s)
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1 These results indicate that ROS generation and NF-kappaB activation are responsible for the down-regulation of PPARalpha and may provide a new mechanism by which intracellular lipid accumulation occurs in skeletal muscle cells. Reactive Oxygen Species peroxisome proliferator activated receptor alpha Mus musculus