Title : Amino acid residues important for substrate specificity of the amino acid permeases Can1p and Gnp1p in Saccharomyces cerevisiae.

Pub. Date : 2001 Nov

PMID : 11746604






2 Functional Relationships(s)
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1 Selection for suppressor mutants that restored growth on L-citrulline led to isolation of 21 mutations in the arginine permease gene CAN1. Citrulline arginine permease CAN1 Saccharomyces cerevisiae S288C
2 L-[(14)C]citrulline uptake measurements confirmed that suppressor mutations in CAN1 conferred uptake of this amino acid, while none of the mutant permeases had lost the ability to transport L-[(14)C]arginine. Citrulline arginine permease CAN1 Saccharomyces cerevisiae S288C