Title : Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin.

Pub. Date : 2001 Oct

PMID : 11562764






2 Functional Relationships(s)
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1 We also found that quercetin markedly increased Cdk-inhibitor p21CIP1/WAF1 protein level after treatment for 48 h or longer, and the induction of p21CIP1/WAF1 increased its association with Cdc2-cyclin B1 complex, however, up-regulation of p53 by quercetin was not observed. Quercetin cyclin dependent kinase 1 Homo sapiens
2 We also found that quercetin markedly increased Cdk-inhibitor p21CIP1/WAF1 protein level after treatment for 48 h or longer, and the induction of p21CIP1/WAF1 increased its association with Cdc2-cyclin B1 complex, however, up-regulation of p53 by quercetin was not observed. Quercetin cyclin dependent kinase 1 Homo sapiens