Title : Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin.

Pub. Date : 2001 Apr

PMID : 11270913






2 Functional Relationships(s)
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1 Because fluvoxamine is an inhibitor of several cytochrome P450 (CYP) enzymes, the authors studied the biotransformation of melatonin and the effects of fluvoxamine on the metabolism of melatonin in vitro using human liver microsomes and recombinant human CYP isoenzymes. Fluvoxamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Because fluvoxamine is an inhibitor of several cytochrome P450 (CYP) enzymes, the authors studied the biotransformation of melatonin and the effects of fluvoxamine on the metabolism of melatonin in vitro using human liver microsomes and recombinant human CYP isoenzymes. Fluvoxamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens