Title : Effects of folate supplementation on two provisional molecular markers of colon cancer: a prospective, randomized trial.

Pub. Date : 2001 Jan

PMID : 11197251






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This study investigated the effect of folate supplementation on genomic DNA methylation and DNA strand breaks in exons 5-8 of the p53 gene of the colonic mucosa, two provisional biomarkers of colon cancer. Folic Acid tumor protein p53 Homo sapiens
2 Similarly, folate supplementation decreased the extent of p53 strand breaks in exons 5-8 at 6 months and 1 yr (p < 0.02), whereas placebo administration was associated with a decrease in the extent of p53 strand breaks only at 1 yr. Folic Acid tumor protein p53 Homo sapiens
3 Similarly, folate supplementation decreased the extent of p53 strand breaks in exons 5-8 at 6 months and 1 yr (p < 0.02), whereas placebo administration was associated with a decrease in the extent of p53 strand breaks only at 1 yr. Folic Acid tumor protein p53 Homo sapiens