Title : Adenosine diphosphate ribose dilates bovine coronary small arteries through apyrase- and 5'-nucleotidase-mediated metabolism.

Pub. Date : 2001 Jan-Feb

PMID : 11173996






2 Functional Relationships(s)
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1 The adenosine production was blocked by the 5"-nucleotidase inhibitor, alpha,beta-methylene adenosine 5"-diphosphate (MADP, 1 mmol/l), which was accompanied by a corresponding accumulation of 5"-AMP. Adenosine 5'-nucleotidase Bos taurus
2 We concluded that ADPR produces vasodilation in small coronary arteries and that the action of ADPR is associated with the adenosine production via an apyrase- and 5"-nucleotidase-mediated metabolism. Adenosine 5'-nucleotidase Bos taurus