Title : Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.

Pub. Date : 2001 Jan

PMID : 11134334






1 Functional Relationships(s)
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1 We analyzed two conditional RAG-1 mutants that affect residues quite close in the primary sequence to an active site amino acid (D600), and we found that they exhibit severely impaired recombination in the presence of certain cleavage site sequences. Gallopamil recombination activating 1 Homo sapiens